The Effects of Solid and Liquid Lipids on the Physicochemical Properties of Nanostructured Lipid Carriers

نویسندگان

چکیده

The aim of this work was to identify from a review current literature the effects lipids used in development Nanostructured Lipid Carriers (NLCs) on physicochemical properties resulting formulation. size solid lipid, affected by molecular weight and complexity structure, tends affect particle final formulation proportionally; higher more complex bigger NLCs. However, there is no straight correlation between structure liquid lipid size. Moreover, seems be ratio which affects size; has been trend increasing when used. Regarding entrapment efficiency, it highly drug its interaction with lipids, as solubility needs high so can stay entrapped within core. There direct type or zeta potential, stability

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Sciences

سال: 2021

ISSN: ['0022-3549', '1520-6017']

DOI: https://doi.org/10.1016/j.xphs.2021.04.012